ea0063gp210 | Diabetes: Pharmacotherapy | ECE2019
Nasiri-Ansari Narjes
, Dimitriadis Georgios K.
, Angelousi Anna
, Tsara Anna
, Lembesis Panayiotis
, Kiaris Hippokrates
, Papavassiliou Athanasios G.
, Randeva Harpal S.
, Kassi Eva
Introduction: Type 2 diabetes mellitus (T2DM) is characterized by progressive impairment/ loss of pancreatic beta cell function Activation of endoplasmic reticulum (ER) stress by glucose variation has been suggested as an essential step towards beta cell dysfunction. Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are widely used in the treatment of T2DM considering their beneficial cardiometabolic sequalae. In the present study, we aimed to investigate the effect of Empag...